Retaining Synaptic AMPARs

نویسندگان

  • Frédéric Jaskolski
  • Stéphane Martin
  • Jeremy M. Henley
چکیده

Endocytosis, exocytosis, and lateral diffusion are key mechanisms for AMPA receptor trafficking. Endocytosis of AMPARs and other postsynaptic proteins has been proposed to occur at specific endocytic zones (EZs), but the mechanisms that regulate this process are not at all clear. In this issue of Neuron, Lu et al. show that correct synaptic EZ positioning requires links between the GTPase dynamin-3 and the Homer/Shank complex.

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عنوان ژورنال:
  • Neuron

دوره 55  شماره 

صفحات  -

تاریخ انتشار 2007